Journal article
Gastric antral vascular ectasia in systemic sclerosis: a study of its epidemiology, disease characteristics and impact on survival
K Morrisroe, D Hansen, W Stevens, J Sahhar, GS Ngian, C Hill, J Roddy, J Walker, S Proudman, M Nikpour
Arthritis Research and Therapy | BMC | Published : 2022
Abstract
Background: To describe the epidemiology, determinants and survival impact of gastric antral vascular ectasia (GAVE) in systemic sclerosis (SSc). Methods: Consecutive SSc patients prospectively enrolled in the Australian Scleroderma Cohort Study (ASCS) were included. Univariable and multivariable logistic regression were used to determine the associations of GAVE with clinical manifestations and serological parameters. Kaplan-Meier (K-M) survival curves were used to estimate survival. Results: The prevalence of GAVE in this SSc cohort of 2039 SSc patients was 10.6% (n = 216) over a median follow-up period of 4.3(1.7–8.4) years. SSc patients with a history of GAVE compared with those without ..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This work was supported by Scleroderma Australia, Arthritis Australia, Actelion Australia, Bayer, CSL Biotherapies, GlaxoSmithKline Australia and Pfizer. KM holds a National Health and Medical Research Council of Australia Investigator Grant (APP1197169). MN holds a National Health and Medical Research Council of Australia Emerging Leadership Level 2 Investigator Grant (APP 1126370).